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In modern therapeutic antibody development, the ability to isolate naturally paired heavy and light chain antibody sequences from B cells is a decisive factor in generating fully human, high-affinity monoclonal antibodies (mAbs). Researchers now rely on innovative B-cell sorting workflows that combi...

In the rapidly evolving field of protein and antibody analysis, achieving exceptional sequence precision is more important than ever. With advances in mass spectrometry and data analytics, the realm of de novo sequencing has experienced pivotal breakthroughs—especially when it comes to the challenge...

In the rapidly evolving field of antibody therapeutics, bispecific antibodies (BsAbs) are gaining momentum thanks to their ability to engage two distinct targets simultaneously. One critical application lies in developing molecules that specifically interfere with receptor-mediated signalling. For e...

The vaccine industry is experiencing its own version of a gold rush—not driven by shortages of primates or skyrocketing sample prices, but by something equally intense: the race to compress the vaccine discovery-to-development cycle. As global pathogens continue to evolve faster than public health s...

Recombinant protein technology has transformed modern biotechnology, enabling the production of highly specific, pure, and functional proteins for a wide range of applications. By inserting a gene of interest into a suitable expression system, scientists can direct host cells such as Escherichia co...

Endothelial cells play a central role in maintaining vascular homeostasis, regulating permeability, and mediating inflammatory responses. Among the various endothelial cell models available, Cynomolgus Monkey HUVEC cells stand out as a valuable system for researchers seeking a closer approximation t...

In the rapidly evolving landscape of cancer immunotherapy, oncolytic virotherapy has emerged as a dynamic force capable of amplifying the immune response against tumors. Once seen merely as a means of direct tumor lysis, oncolytic viruses (OVs) are now recognized for their ability to reshape the tum...

The rise of targeted protein degradation (TPD) has opened a new chapter in modern drug discovery. Unlike traditional inhibitors that merely block protein activity, degraders work by eliminating disease-causing proteins altogether through the ubiquitin–proteasome system. Behind this elegant mechanism...

When the first mRNA vaccines made global headlines, they didn't just signal a medical milestone—they sparked a revolution. Scientists suddenly realized that mRNA wasn't only a fleeting molecule of genetic code but a programmable platform capable of driving the future of gene therapy. Yet, unlocking ...

In the rapidly evolving field of gene therapy, high-quality plasmids play a crucial role as the backbone of genetic constructs. Efficient production of these plasmids is essential for preclinical research, clinical trials, and large-scale therapeutic applications. This is where contract development ...